MODIFICATION OF THE FOXP3 TRANSCRIPTION FACTOR PRINCIPALLY AFFECTS INDUCIBLE T REGULATORY CELLS IN A MODEL OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS.

Modification of the FoxP3 transcription factor principally affects inducible T regulatory cells in a model of experimental autoimmune encephalomyelitis.

T regulatory (Treg) cells expressing the transcription factor FoxP3 play a key role in protection against autoimmune disease.GFP-FoxP3 reporter mice have been used widely to study the induction, function and stability of both thymically- and peripherally-induced Treg cells.The N-terminal modification of FoxP3, however, affects its interaction with

read more


Blood-based tri-hybrid nanofluid flow through a porous channel with the impact of thermal radiation used in drug administration

In recent trends science and technology is developed due to the utilization of modern devices of high quality and their longevity with potential efficiency.The implementation of nanoparticles now characterizes the effectiveness and efficiency.Specifically, in biomedical research drug delivery into the target, hyperthermia treatment for cancer, Bott

read more